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It said blood spots under the skin might also be present, either as spots or dots or on larger areas. Dermoscopy showed dotted and linear vessels forming a network on a yellowish background, with some whitish peripheral scales (Figure 3A). To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. This patch is the herald or mother patch. While it can spread all over the entire body, PR usually favors the trunk, says Christina Lam, an assistant professor of dermatology at Boston University School of Medicine and dermatologist at Boston Medical Center. Pityriasis is linked mainly with herpesviruses 6 and 7; only a . Cutis. Khalili M, Abtahi-Naeini B, Rastegarnasab F, Afshar K. Clin Case Rep. 2022 Jul 19;10(7):e6096. Epub 2022 Jun 21. (2021) 85:4655. Atypical pityriasis rosea associated with mRNA COVID19 vaccine E. Bostan, Adam Jarbou Published 29 September 2021 Medicine Journal of Medical Virology Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of Covid-19. Br J Dermatol 2020; 183: 431442. Oily fish, such as mackerel, salmon or sardines. eCollection 2022. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. It should clear your body in six to eight weeks. Pityriasis rosea (pih-tuh-RY-uh-sis ROH-zee-uh) is a common skin condition that causes patches of your skin to develop raised, scaly rashes. Medicines (Basel). MeSH Learning points: Numerous scattered erythematous plaques with fine scale oriented along skin cleavage, Herald patch of pityriasis rosea. Br J Dermatol. Numerous scattered erythematous plaques with fine scale oriented along skin cleavage lines, most appreciable on the upper portion of the chest. Disclaimer. Epub 2022 Jul 19. Clinical findings of pityriasis rosealike, Clinical findings of pityriasis rosealike eruption in the patients. J Eur Acad Dermatol Venereol. (d) Patient 2: Closeup of plaques, with the hyperpigmented centre and trailing scale. Rationale: Accessibility 8 In some cases, antibodies against HHV6/7 as well as viral DNA in plasma and PBMCs were detected. Nevertheless, she did not present with fever or respiratory tract symptoms. J Eur Acad Dermatol Venereol 2020;34:e2123. Few scattered dyskeratotic keratinocytes are seen in the lower epidermis. -, Busto-Leis J.M., Servera-Negre G., Mayor-Ibarguren A., et al. KL and KP collated resources. National Library of Medicine A more recent letter in the International Journal of Dermatology reported a "unique case of pityriasis rosea following administration of mRNA COVID-19 vaccine." Ramot Y, Nanova K, Faitatziadou SM, Assab DA, Berkun Y, Zlotogorski A. J Dtsch Dermatol Ges. Pityriasis rosea isnt a sexually transmitted disease or infection (STD or STI). Six cases of pityriasis rosea following SARS-CoV-2 vaccination with BNT162b2. 2021;35(8):e489e491. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Epub 2022 Feb 9. Global prevalence and clinical manifestations of cutaneous adverse reactions following COVID-19 vaccination: A systematic review and meta-analysis. This site needs JavaScript to work properly. 2022 Nov 1;43(6):555-558. doi: 10.2500/aap.2022.43.220058. This site needs JavaScript to work properly. We present a case of a pityriasis rosea-like rash occurring after Pfizer COVID-19 vaccination and review cases of pityriasis rosea (PR)/PR-like eruption (PR-LE) after mRNA COVID-19 vaccine published in the medical literature. Is there a prescription cream or ointment that you can prescribe? Suchonwanit P, Leerunyakul K, Kositkuljorn C. Diagnostic and prognostic values of cutaneous manifestations in COVID-19. 9 , 10 These findings suggest that immuneinduced viral reactivation - rather than doi: 10.1111/jdv.17342, 5. As vaccine reactogenicity reports continue to surface, dermatologists and other health care providers should understand the landscape of the latest cutaneous reactions to guide and address patients' concerns. Unauthorized use of these marks is strictly prohibited. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine. Epub 2022 Jun 8. Clinical manifestations and histopathologic findings of reported patients with pityriasis-rosea like eruptions following COVID-19 vaccination. Herzum A, Trave I, D'Agostino F, Burlando M, Cozzani E, Parodi A. Clin Exp Vaccine Res. Dermatol Ther. Lawley LP, McCall CO, Lawley TJ. In addition to COVID-19 vaccination, she was currently taking medications (i.e., levetiracetam and thyroxin) for glioblastoma, and the two drugs had been prescribed for approximately nine months. Pityriasis rosea following SARS-CoV-2 vaccination: A case series. The authors suggest more research is necessary. Unable to load your collection due to an error, Unable to load your delegates due to an error. Moreover, central dusky-red erythematous was observed on some plaques (Figure 2A). How can you tell that I have pityriasis rosea? A 3-cm oval plaque with peripheral scale, larger than the other lesions, was present on the inferior portion of the right breast. 2021;185(2):e34. Diagnoses: Em Rata Just Debuted a Chic Italian Bob With Baby Bangs. J Formos Med Assoc. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Here, we describe a case of PR-like eruption following ChAdOx1 nCoV-19 (AZD1222) vaccination in a Thai patient with glioblastoma. If you have pityriasis rosea, it can generally be well-managed without any treatment. An official website of the United States government. Fortunately, PR-like eruption is responsive to topical corticosteroids without any systemic adverse effects. Dermatol Res Pract. Appointments 216.444.5725 Appointments & Locations Request an Appointment Pityriasis rosea and pityriasis rosea-like eruptions after COVID-19 vaccines. Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review. I tell my patient to use a gentle non-soap cleanser." Your California Privacy Rights. 2020 Jul;33(4):e13730. (b) haematoxylineosin, original magnification 20. Clipboard, Search History, and several other advanced features are temporarily unavailable. KL drafted the original manuscript. I video-chatted with my dermatologist who asked a few questions: Did I have body aches or flu-like symptoms? Front. 2021 May;62(2):e333-e334. Accessibility Bookshelf The average time between vaccination and rash onset is 10 days, and most patients experience pruritus (70%). Would you like email updates of new search results? The https:// ensures that you are connecting to the Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. I figured a very determined mosquito had snuck into my room and attacked me through my tank top. 2021;185(2):e34. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. Careers. Before Even though it is benign, it can cause substantial. These findings were consistent with a diagnosis of PR-like eruption. Figure 3. And the itch usually only lasts for a few days mine finally let up around day seven but the rash can leave behind dark marks that eventually resolve on their own, Lam says. (No.) Clipboard, Search History, and several other advanced features are temporarily unavailable. If I dont have pityriasis rosea, what other skin condition might I have? Global prevalence and clinical manifestations of cutaneous adverse reactions following COVID-19 vaccination: A systematic review and meta-analysis. Interventions: National Library of Medicine Children often get infected when someone sneezes or kisses them. One week before the rash, respiratory tract infection symptomatology was observed by the patient. Those ensuing spots like the circle of dots that erupted on my back a day after the initial raised welt appeared typically resemble a Christmas tree-like formation. Authors B M Cyrenne 1 , F Al-Mohammedi 1 , J G DeKoven 1 , R Alhusayen 1 Affiliation Treatment with topical 0.1% triamcinolone acetonide twice per day showed partial response after seven days. doi: 10.1111/dth.13878, 10. In: Jameson J, Fauci AS, Kasper DL, et al., eds. Federal government websites often end in .gov or .mil. doi: 10.1111/dth.13650, 7. J Med Virol 2021; 93: 18501851. Your symptoms dont improve after treatment. The site is secure. She diagnosed it as pityriasis rosea, a benign but frustratingly itchy rash that in her words just happens sometimes. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. Federal government websites often end in .gov or .mil. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. A spectrum of cutaneous reactions to SARs-CoV-2 (COVID-19) vaccines have been reported in the literature. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. Foods that have anti-inflammatory properties include: Foods that may increase inflammation include: There isnt any way to prevent pityriasis rosea. Accessibility Some people who have had cosmetic fillers used to remove . Sriphojanart T, Khunkhet S, Suchonwanit P. A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata. This article presents a case of PR in a 66-year-old black male 1 week after administration of the Pfizer-BioNTech COVID-19 vaccine. Involvement of the oral mucosa has also been reported in as many as 50% of all cases (11). Birlutiu V, Dobritoiu ES, Lupu CD, Herteliu C, Birlutiu RM, Dragomirescu D, Vorovenci A. A few days later, the cluster came: Ten little dots arranged themselves in a perfect alien-like crop circle on my upper back, and they itched so much that I scratched them raw. The .gov means its official. The herald patch is the telltale sign that your rash could be PR, but there are other common (though not universal) symptoms as well. The study said the appearance was similar to pityriasis rosea, a common skin condition. While annoyingly itchy, the rash does not cause any serious long-term side effects and is not contagious, unlike the diseases these vaccines protect against. (2021) 93:18501. Characterization of the inflammatory cell infiltrate in herald patches and fully developed eruptions of pityriasis rosea. Generalized Papulovesicular Eruption as a Side Effect of the Pfizer-BioNTech COVID-19 Vaccine. Herein, we are reporting a unique. We evaluated the clinical and pathologic spectrum of mucocutaneous reactions following COVID-19 vaccines, observed consecutively within three large tertiary Centers of the Metropolitan City of Milan . If you develop symptoms of pityriasis rosea while pregnant, contact your healthcare provider right away. J Investig Dermatol 2005;124:123440. doi: 10.1111/bjd.20143. Pityriasis Rosea. Epub 2020 Jun 5. Due to the temporal relationship between vaccination and onset of rash, COVID-19 vaccination was the most likely etiology. They were found on hands and feet, showing up as red or purple spots caused by bleeding under the skin. Lastly, Hartman says PR can present differently in patients with darker skin: "The characteristic erythematous plaques may appear more hyperpigmented or violaceous in darker skin types. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance. Bookshelf The exanthem was self-limited in both patients over a period of a month. According to King, an in-person skin exam is usually enough to make an accurate diagnosis, though a biopsy or blood work may be necessary for some. NCI CPTC Antibody Characterization Program. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Epub 2022 Jun 21. Med. The https:// ensures that you are connecting to the However, several adverse effects of COVID-19 vaccination have been identified. Clipboard, Search History, and several other advanced features are temporarily unavailable. Pityriasis Lichenoides. This site needs JavaScript to work properly. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event. (2021) 35:e5468. 2021 Nov 2;17(11):4097-4098. doi: 10.1080/21645515.2021.1963173. This rash is thought to be caused by a virus. Before SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. HHS Vulnerability Disclosure, Help Int J Dermatol. Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. J Eur Acad Dermatol Venereol. All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. Figure 2. Epub 2020 Nov 20. Borgia F, Li Pomi F, Alessandrello C, Vaccaro M, Pioggia G, Gangemi S. J Dermatol. Although histopathologic characteristics of PR are also observed in PR-like lesions, the presence of dyskeratotic keratinocytes, interface dermatitis, and eosinophilic infiltration in the dermis may be more prominent in PR-like eruptions (11). J Am Acad Dermatol. A woman. eCollection 2022 Jul. Dermatology. Adya KA, Inamadar AC, Albadri W. Post Covid-19 vaccination papulovesicular pityriasis rosea-like eruption in a young male. 2022 Oct 4;15:2117-2127. doi: 10.2147/CCID.S371630. Ad Choices. (Within two days, and still no.) sharing sensitive information, make sure youre on a federal The site is secure. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. JAAD Case Rep. (2018) 4:8001. Do the medications have any side effects? doi: 10.1111/jdv.17498. However, if you experience any symptoms, therapy can provide relief. Epub 2022 Jan 5. A virus may cause pityriasis rosea, but experts aren't sure. Keywords: 2022 Aug;35(8):e15601. Cutis. Unfortunately, due to her deteriorating neurologic status, her associated symptoms were not evaluated properly. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases. Vaccinations have been identified to rarely cause several cutaneous reactions. Now watch a pro surfer's entire daily routine: Follow Allure onInstagram andTwitter, orsubscribe to our newsletter to stay up to date on all things beauty. Epub 2022 Feb 9. | Pityriasis Rosea, COVID-19 and . doi: 10.1111/bjd.20143. Influenza viruses and vaccines have triggered pityriasis rosea in some cases.". 2021;85(1):4655. Before Pityriasis rosea is also known as Christmas tree rash. How do dermatologists treat pityriasis rosea? You may develop a raised, discolored, circular or oval-shaped patch that ranges from 1 to 6 centimeters (cm). 2022 Aug 11;9(8):43. doi: 10.3390/medicines9080043. Moreover, while dermoscopy may facilitate the diagnosis of PR, its utility for atypical PR or PR-like lesions is still limited. This site needs JavaScript to work properly. Numerous scattered erythematous, Pityriasis rosea. The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author/s. Drago F, Ciccarese G, Rebora A, et al. Keywords: adverse effect, coronavirus, cutaneous eruptions, immunization, pityriasis rosea, SARS-CoV-2, vaccine, case report, Citation: Leerunyakul K, Pakornphadungsit K and Suchonwanit P (2021) Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. Br J Dermatol. Accessibility Women and young people are most likely to have these reactions. (a) Patient 1: Thin, Histopathological findings of pityriasis rosealike, Histopathological findings of pityriasis rosealike eruption in patient 1. Epub 2021 May 29. -, Neoh CY, Tan AW, Mohamed K, et al. "Any type of stress on the body can sometimes [cause them, and] any vaccine, not just the COVID one.". Herald patch in the right hypochondrium followed by typical oval-shaped secondary plaques, Pityriasis rosea lesions on the upper extremities, MeSH Careers. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291919/). Clinical aspect of the lesions after 7 days of treatment. doi: 10.7759/cureus.27108. Disclaimer. Would you like email updates of new search results? It was found on younger COVID-19 patients suffering milder forms of the virus. Bethesda, MD 20894, Web Policies J Eur Acad Dermatol Venereol 2020; 34: e436-e437. Some studies have identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins on endothelial cells and lymphocytes from PR-like lesions, consistent with direct viral invasion (3, 4). Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection J Eur Acad Dermatol Venereol. A team of researchers . Would you like email updates of new search results? HHS Vulnerability Disclosure, Help You may initially develop a fever, headache or upper respiratory infection. 2022 Dec;9:127. doi: 10.1016/j.jdin.2022.03.018. 2022 Aug;87(2):295. doi: 10.1016/j.jaad.2022.06.036. eCollection 2022. Federal government websites often end in .gov or .mil. In some cases, central hyperpigmentation was identified. Europe PMC is an archive of life sciences journal literature. Copyright 2021 Leerunyakul, Pakornphadungsit and Suchonwanit. Disclaimer. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. JAAD Int. doi: 10.1111/jdv.17316. "There's some emerging data where there are certain skin rashes that seem to be more associated with the COVID vaccine, and pityriasis rosea is one them. See this image and copyright information in PMC. Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. 7 Articles, This article is part of the Research Topic, Creative Commons Attribution License (CC BY), Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Advertising on our site helps support our mission. Pityriasis rosea is a common condition that causes discolored patches on your skin. Vaccination is one of the cornerstones in the efforts towards ending the coronavirus disease 2019 (COVID-19) pandemic. At first, I thought it was a mosquito bite. Histopathological findings of pityriasis rosealike eruption in patient 1. Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, et al. Pityriasis rosea and ringworm look similar. Among 171 laboratory-confirmed COVID-19 patients with cutaneous manifestations from the registry, the most commonly reported were morbilliform rash (22 percent), pernio-like acral lesions (18 percent), urticaria (16 percent), macular erythema (13 percent), vesicular eruption (11 percent), papulosquamous eruption (9.9 percent), and retiform Lessons: Dtsch Arztebl Int. We do not endorse non-Cleveland Clinic products or services. PR also tends to occur in patients between the ages of 10 to 35 that are usually otherwise healthy, Lam says. While home remedies are safe for most people, its a good idea to check with your healthcare provider before trying some of the following options. What started as a single, quarter-inch raised welt on my left rib cage eventually morphed into two, then four. You may be at risk of developing an allergic reaction on your skin. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. An official website of the United States government. 2022 Jul 8;101(27):e29823. doi: 10.7759/cureus.22414. Bethesda, MD 20894, Web Policies sharing sensitive information, make sure youre on a federal For instance, the rash sometimes appears only under the arms or on the flanks. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Epub 2022 Oct 17. "Other treatments including phototherapy or oral medications can be considered for extensive or persistent cases, [and] some small case studies support the use of oral antivirals like acyclovir or oral anti-inflammatory antibiotics erythromycin," King explains. They indicate that eight types of rash could be signs of Covid-19, including red toes and fingers, chest eczema and pityriasis rosea (scroll down for the full list). Skin lesions appeared in a 49-year-old female 8 days after the first dose of the BNT162b2 mRNA vaccine and in a 53-year-old male 7 days after the second dose of the same vaccine. (2019) 34:185764. Temiz SA, Abdelmaksoud A, Dursun R, Durmaz K, Sadoughifar R, Hasan A. J Cosmet Dermatol. Use of this site constitutes acceptance of our About one to two weeks later, discolored circular or oval-shaped patches appear in groups near the herald patch. Adverse cutaneous reactions following COVID-19 vaccines have increased, highlighting not only how SARS-CoV-2 infection but also COVID-19 vaccines may induce adverse cutaneous manifestations. "In studies, between 2 and 3 percent of people develop the disease again. 2021;35(8):e489e491. Clin Dermatol. The Covid Symptom Study. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. Leerunyakul K, Pakornphadungsit K, Suchonwanit P. Front Med (Lausanne). These types cannot cause cold sores or genital herpes. Cutis. Human herpesvirus-6, -7, and Epstein-Barr virus reactivation in pityriasis rosea during COVID-19. Herald patch of pityriasis rosea. Many Americans become infected with them at an early age. Treatment with topical 0.1% triamcinolone acetonide twice daily showed partial response after seven days. doi: 10.1016/j.jdcr.2018.04.002, 12. Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders. 2022 Mar 15;10(3):624. doi: 10.3390/microorganisms10030624. 2022 Jul 21;14(7):e27108. (2006) 12:1. doi: 10.5070/D380D8301D, 11. "It's usually not from head to toe that's more atypical but there are some people that get it more in the groin area or in the armpit rather than on the trunk predominantly, which is just a variant.". FOIA Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. Fried foods, including many fast-food items. Pityriasis means scaly, and rosea means pink, but the rashes may look red, gray, brown or purple. Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. 2021 Oct;20(10):3080-3084. doi: 10.1111/jocd.14372. Luckily, it's not contagious. Conflicts of Interests: The authors declare there are no competing interests. Last reviewed by a Cleveland Clinic medical professional on 06/17/2022. The patients/participants provided their written informed consent to participate in this study. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. J Eur Acad Dermatol Venereol. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Epub 2021 Nov 2. 2021 Sep;35 (9):e546-e548. HHS Vulnerability Disclosure, Help Under the treatment that was initiated a partial remission of the lesions after 7 days was observed. . Unauthorized use of these marks is strictly prohibited. The site is secure. sharing sensitive information, make sure youre on a federal Pityriasis rosea developing after COVID-19 vaccination. Recurrent and persistent pityriasis rosea: an atypical case presentation. Global prevalence and clinical manifestations of cutaneous adverse reactions following COVID-19 vaccination: A systematic review and meta-analysis. -, Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, Franco-Marquez R, Arvizu-Rivera RI. Why not? 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Additional evidence that pityriasis rosea is associated with reactivation of human herpesvirus-6 and -7. and transmitted securely. MeSH National Library of Medicine A 3-cm oval plaque with peripheral scale, larger, MeSH Epub 2022 Jan 5. The .gov means its official. MeSH Disclaimer. (2017) 9:7399. doi: 10.4081/dr.2017.7399, 17. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. 2021 Sep;60(9):1150-1151.doi: 10.1111/ijd.15700. Int J Dermatol. 78 PDF Pityriasis rosea following CoronaVac COVID19 vaccination: a case report Elin Akda, N. Ilter, B. t, . Erdem -, Broccolo F, Drago F, Careddu AM, et al. J Am Acad Dermatol. 2023 Cond Nast. Atzori L, Pinna AL, Ferreli C, Aste N. Pityriasis rosea-like adverse reaction: review of the literature and experience of an Italian drug-surveillance center. Br J Dermatol. However, in cases of atypical PR, it may present with erythema multiforme-like lesions and purpura (5). Previously, PR has been reported in temporal association with various viral inoculations. Disseminated erythematous-papulosquamous lesions, with right laterocervical herald patch (clinical aspect on admission). The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. However, the studies dont conclusively prove that COVID-19 causes pityriasis rosea. Yes, There Is a Correct Order for Everything You Do in the Shower, Each Zodiac Sign's Unique Personality Traits, Swoopy 1960s Hair Was Everywhere at the SAG Awards, Christina Aguilera Opened Up About Getting Injections and Why She Doesn't Care If People Judge Her, "I think we all can rely on a little help. An official website of the United States government. SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. An official website of the United States government. Busto-Leis JM, Servera-Negre G, Mayor-Ibarguren A, Sendagorta-Cuds E, Feito-Rodrguez M, Nuo-Gonzlez A, et al. Clipboard, Search History, and several other advanced features are temporarily unavailable. Published by Elsevier Inc. Pityriasis rosea. Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. government site. FOIA eCollection 2022. Careers. Ethical review and approval was not required for the study on human participants in accordance with the local legislation and institutional requirements. 2022 Sep;21(9):3692-3703. doi: 10.1111/jocd.15209. Epub 2022 Jun 13. The .gov means its official. Human herpesviruses 6 and 7 are common. J Eur Acad Dermatol Venereol 2020;34:e4367. Curr Dermatol Rep. 2022;11(4):289-312. doi: 10.1007/s13671-022-00370-9. -, Johansen M, Chisolm SS, Aspey LD, Brahmbhatt M. Pityriasis rosea in otherwise asymptomatic confirmed COVID-19-positive patients: a report of 2 cases. Histopathologic examination revealed epidermal focal spongiosis, interface dermatitis with necrotic keratinocytes, perivascular lymphocytic infiltration, and few eosinophilic infiltrations in the superficial dermis (Figures 3B,C). -, Mahajan K, Relhan V, Relhan AK, et al. The .gov means its official. You also wont have permanent scarring or other damage to your skin. Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature. doi: 10.1097/MD.0000000000029823. In: Papadakis MA, McPhee SJ, Bernstein J., eds. One case of pityriasis rosea is reported in a patient infected with COVID19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy.